Metro-Goldwyn-Mayer released a motion picture version of Madame Curie in 1943. Produced by Sidney Franklin, directed by Mervyn LeRoy, and starring Greer Garson and Walter Pidgeon, the film earned Academy Award nominations for best picture, best actor, photography, and music. The movie resembles the book with its dignified tone and analytical orientation, but it cannot maintain the exclusive standards for reproducing dialogue or offer the intimate insights of extensively quoted letters.

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